Oxacillin

(CC) Image: David E. Volk
Oxacillin.

Oxacillin, sold under the brand name Bactocill®, is a penicillin beta-lactam type of antibiotic similar to flucloxacillin used in resistant staphylococci infections. It is active against gram-positive bacteria and some gram-negative bacteria. Like other penicillin-like antibiotics, it functions by interfering with the last stage of bacterial cell wall synthesis and leads to autolysis of the bacteria cells. It is stable against hydrolysis from beta-lactamases, including penicillinases, and cephalosporinases.

Its IUPAC chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl1,2-oxazole-4-carbonyl)amino]-7-oxo-4- thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid and it has molecular formula C₁₉H₁₉N₃O₅S.

External links

• Oxacillin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
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