Oxacillin: Difference between revisions

From Citizendium
Jump to navigation Jump to search
imported>David E. Volk
imported>David E. Volk
(Capitalize Gram-+/- and add Chem infobox)
Line 1: Line 1:
{{subpages}}
{{subpages}}
[[Image:Oxacillin structure.jpg|right|thumb|250px|{{#ifexist:Template:Oxacillin structure.jpg/credit|{{Oxacillin structure.jpg/credit}}<br/>|}}Oxacillin.]]
'''Oxacillin''', sold under the brand name '''Bactocill®''', is a penicillin beta-lactam type of antibiotic similar to flucloxacillin used in resistant staphylococci infections.  It is active against gram-positive bacteria and some gram-negative bacteria.  Like other penicillin-like antibiotics, it functions by interfering with the last stage of bacterial cell wall synthesis and leads to [[autolysis]] of the bacteria cells.  It is stable against hydrolysis from beta-[[lactamase]]s, including [[penicillinase]]s, and [[cephalosporinase]]s.


{{Chem infobox
|align=right
|image=[[Image:Oxacillin structure.jpg|right|thumb|250px|{{#ifexist:Template:Oxacillin structure.jpg/credit|{{Oxacillin structure.jpg/credit}}<br/>|}}]] 
|width=250px
|molname=oxacillin
|synonyms='''Bactocill®'''
|molformula= C<sub>19</sub>H<sub>19</sub>N<sub>3</sub>O<sub>5</sub>S
|molmass= 401.4363
|uses= antibiotic drug
|properties=beta-lactam
|hazards=see drug interactions
|iupac= see chemistry section
|casnumber=66-79-5
}}
'''Oxacillin''', sold under the brand name '''Bactocill®''', is a penicillin beta-lactam type of antibiotic similar to flucloxacillin used in resistant staphylococci infections.  It is active against Gram-positive bacteria and some Gram-negative bacteria.  Like other penicillin-like antibiotics, it functions by interfering with the last stage of bacterial cell wall synthesis and leads to [[autolysis]] of the bacteria cells.  It is stable against hydrolysis from beta-[[lactamase]]s, including [[penicillinase]]s, and [[cephalosporinase]]s.
== Chemistry ==
Its IUPAC chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl1,2-oxazole-4-carbonyl)amino]-7-oxo-4-
Its IUPAC chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl1,2-oxazole-4-carbonyl)amino]-7-oxo-4-
thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid and it has molecular formula C<sub>19</sub>H<sub>19</sub>N<sub>3</sub>O<sub>5</sub>S.
thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid and it has molecular formula C<sub>19</sub>H<sub>19</sub>N<sub>3</sub>O<sub>5</sub>S, giving it a molecular mass of 401.4363 g/mol.


== External links ==
== External links ==

Revision as of 12:17, 3 April 2008

This article is a stub and thus not approved.
 Main Article
 Discussion
Related Articles  [?]
Bibliography  [?]
External Links  [?]
Citable Version  [?]
 
https://en.citizendium.org/wiki/index.php?title=Oxacillin&printable=yes
This editable Main Article is under development and subject to a disclaimer.
(CC) Image: David E. Volk
oxacillin
IUPAC name: see chemistry section
Synonyms: Bactocill®
Formula: C19H19N3O5S
 Uses: antibiotic drug
 Properties: beta-lactam
 Hazards: see drug interactions
Mass (g/mol): CAS #:
401.4363 66-79-5


Oxacillin, sold under the brand name Bactocill®, is a penicillin beta-lactam type of antibiotic similar to flucloxacillin used in resistant staphylococci infections. It is active against Gram-positive bacteria and some Gram-negative bacteria. Like other penicillin-like antibiotics, it functions by interfering with the last stage of bacterial cell wall synthesis and leads to autolysis of the bacteria cells. It is stable against hydrolysis from beta-lactamases, including penicillinases, and cephalosporinases.

Chemistry

Its IUPAC chemical name is (2S,5R,6R)-3,3-dimethyl-6-[(5-methyl-3-phenyl1,2-oxazole-4-carbonyl)amino]-7-oxo-4- thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid and it has molecular formula C19H19N3O5S, giving it a molecular mass of 401.4363 g/mol.

External links

Retrieved from "https://citizendium.org/wiki/index.php?title=Oxacillin&oldid=406025"