Protease inhibitor: Difference between revisions
Jump to navigation
Jump to search
imported>David E. Volk No edit summary |
imported>David E. Volk mNo edit summary |
||
| Line 6: | Line 6: | ||
== protease inhibitors used to treat [[HIV]]/[[AIDS]] == | == protease inhibitors used to treat [[HIV]]/[[AIDS]] == | ||
* [[amprenavir]] | |||
* [[nelfinavir]] | * [[nelfinavir]] | ||
| Line 14: | Line 16: | ||
== Other protease inhibitors == | == Other protease inhibitors == | ||
Revision as of 09:46, 29 January 2008
A protease inhibitor is a chemical compound that inhibits the functions of proteases to control viral infections, especially so for the treatment of HIV/AIDS, but also for the treatment of other viruses, such as chicken pox. All cells have protease enzymes that cleavie cellular proteins, which is required for normal cell live cycles. By distrupting the use of natural proteases within the cell, the use of protease inhibitors causes severe side effects, and because the half-life of many protease inhibitors is short (3-5 hr.) the drugs must given every 4-6 hours. Protease inhibitors are often structural mimics of the proteins active (binding) sites on which the proteases would normally bind.
protease inhibitors used to treat HIV/AIDS