Fluvastatin: Difference between revisions
imported>David E. Volk (New page: {{subpages}} [[Image:Fluvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Fluvastatin structure.jpg/credit|{{Fluvastatin structure.jpg/credit}}<br/>|}}Fluvastatin, a class II st...) |
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[[Image:Fluvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Fluvastatin structure.jpg/credit|{{Fluvastatin structure.jpg/credit}}<br/>|}}Fluvastatin, a class II statin.]] | [[Image:Fluvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Fluvastatin structure.jpg/credit|{{Fluvastatin structure.jpg/credit}}<br/>|}}Fluvastatin, a class II statin.]] | ||
'''Fluvastatin''', also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and fluindostatin, is a class II statin used for the treatment of high cholesterol levels ([[hypercholesterolemia]]), the prevention of [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish [[atherosclerosis|arterial plaque]] formation. It is used to reduce levels of total cholesterol, LDL-cholesterol, [[triglyceride]]s and apo B. It was the first synthetically derived [[ | '''Fluvastatin''', also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and fluindostatin, is a class II statin used for the treatment of high cholesterol levels ([[hypercholesterolemia]]), the prevention of [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish [[atherosclerosis|arterial plaque]] formation. It is used to reduce levels of total cholesterol, LDL-cholesterol, [[triglyceride]]s and apo B. It was the first synthetically derived [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] and like the other class II statins, [[carivastin]], [[atorvastatin]] and [[rosuvastatin]], it is based on an [[indole]] ring structure rather than the naphthalene ring system present in the class I statins [[mevastatin]], [[lovastatin]], [[pravastatin]] and [[simvastatin]]. Suppression of HMG-CoA reductase decreases production of [[mevalonate]], a key chemical precursor of [[cholesterol]]. | ||
Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>24</sub>H<sub>26</sub>FNO<sub>4</sub>. | Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>24</sub>H<sub>26</sub>FNO<sub>4</sub>. | ||
Revision as of 11:28, 24 January 2008
Fluvastatin, also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and fluindostatin, is a class II statin used for the treatment of high cholesterol levels (hypercholesterolemia), the prevention of heart attacks and strokes, and to diminish arterial plaque formation. It is used to reduce levels of total cholesterol, LDL-cholesterol, triglycerides and apo B. It was the first synthetically derived HMG-CoA reductase inhibitor and like the other class II statins, carivastin, atorvastatin and rosuvastatin, it is based on an indole ring structure rather than the naphthalene ring system present in the class I statins mevastatin, lovastatin, pravastatin and simvastatin. Suppression of HMG-CoA reductase decreases production of mevalonate, a key chemical precursor of cholesterol.
Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C24H26FNO4.
brand names
Fluvastatin is sold in the following brand name products.
- Cranoc
- Lescol
- Lescol XL
- Canef