Cirrhosis: Difference between revisions

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===Hepatorenal syndrome===
===Hepatorenal syndrome===
Octreotide/Midodrine combined therapy can help according to a [[randomized controlled trial]].<ref name="pmid17235705">{{cite journal |author=Esrailian E, Pantangco ER, Kyulo NL, Hu KQ, Runyon BA |title=Octreotide/Midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome |journal=Dig. Dis. Sci. |volume=52 |issue=3 |pages=742–8 |year=2007 |pmid=17235705 |doi=10.1007/s10620-006-9312-0 |issn=}}</ref>
{{main|Hepatorenal syndrome}}


==Prognosis==
==Prognosis==

Revision as of 05:57, 18 June 2008

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Cirrhosis is a "liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules."[1]

Complications

Ascites

For more information, see: Ascites.


Esophageal varices

Patients with a platelet count of less than 40 and a palpable spleen are more likely to have esophageal varices.[2]

Hepatic encephalopathy

For more information, see: Hepatic encephalopathy.


Hepatorenal syndrome

For more information, see: Hepatorenal syndrome.


Prognosis

MELD Score

For more information, see: MELD Score.

The MELD Score can help predict mortality. An online calculator is available.

References

  1. Anonymous. Liver cirrhosis. National Library of Medicine. Retrieved on 2008-01-07.
  2. Sharma SK, Aggarwal R (2007). "Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parameters". J. Gastroenterol. Hepatol. 22 (11): 1909–15. DOI:10.1111/j.1440-1746.2006.04501.x. PMID 17914969. Research Blogging.