Acetylcholinesterase: Difference between revisions
Jump to navigation
Jump to search
imported>Howard C. Berkowitz No edit summary |
mNo edit summary |
||
| (One intermediate revision by one other user not shown) | |||
| Line 1: | Line 1: | ||
{{subpages}} | {{subpages}} | ||
In [[biochemistry]], '''acetylcholinesterase''' is an "[[enzyme]] that catalyzes the hydrolysis of [[acetylcholine]] to [[choline]] and [[acetate]]. In the [[central nervous system|CNS]], this enzyme plays a role in the function of peripheral [[neuromuscular junction]]s."<ref>{{MeSH}}</ref> It causes muscle to | In [[biochemistry]], '''acetylcholinesterase''' is an "[[enzyme]] that catalyzes the hydrolysis of [[acetylcholine]] to [[choline]] and [[acetate]]. In the [[central nervous system|CNS]], this enzyme plays a role in the function of peripheral [[neuromuscular junction]]s."<ref>{{MeSH}}</ref> It causes muscle, stimulated by acetylcholine, to relax. | ||
==Medical uses== | ==Medical uses== | ||
| Line 7: | Line 7: | ||
Cholinesterase inhibition is the mechanism of toxicity of "[[nerve gas]]" [[chemical weapon]]s and insecticides. Such poisoning is initially treated with [[atropine]]. | Cholinesterase inhibition is the mechanism of toxicity of "[[nerve gas]]" [[chemical weapon]]s and insecticides. Such poisoning is initially treated with [[atropine]]. | ||
==References== | ==References== | ||
<references/> | <references/>[[Category:Suggestion Bot Tag]] | ||
Latest revision as of 06:00, 6 July 2024
In biochemistry, acetylcholinesterase is an "enzyme that catalyzes the hydrolysis of acetylcholine to choline and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions."[1] It causes muscle, stimulated by acetylcholine, to relax.
Medical uses
Cholinesterase inhibitors may be used for the treatment of disorders of gastrointestinal tract, urinary bladder, the eye, skeletal muscles, and also dementia. Cholinesterase inhibitors may stimulate the parasympathetic nervous system.
Cholinesterase inhibition is the mechanism of toxicity of "nerve gas" chemical weapons and insecticides. Such poisoning is initially treated with atropine.
References
- ↑ Anonymous (2024), Acetylcholinesterase (English). Medical Subject Headings. U.S. National Library of Medicine.