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*Summary prepared by Bruce McEwen and Teresa Seeman in collaboration with the Allostatic Load Working Group. Last revised 1999.
*Summary prepared by Bruce McEwen and Teresa Seeman in collaboration with the Allostatic Load Working Group. Last revised 1999.
*Chapter Contents:
*Chapter Contents:
:*Introduction  
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Introduction Introduction]
:*Where Stress Fits In
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Stress Where Stress Fits In]
:*Allostasis and Allostatic Load
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Allostasis Allostasis and Allostatic Load]
:*Allostatic Load Requires Understanding of Physiological Mechanisms
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Mechanismshttp://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Mechanisms Allostatic Load Requires Understanding of Physiological Mechanisms]
:*Validation of Allostatic Load
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Validationhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Validation Validation of Allostatic Load]
:*Further Refinement of Allostatic Load
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Refinementhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Refinement Further Refinement of Allostatic Load]
:*References
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#Referenceshttp://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html#References References]


:———
:———


*[http://www.macses.ucsf.edu/Research/Allostatic/chapters.html John D. and Catherine T. MacArthur Research Network on Socioeconomic Status and Health: Allostatic Load and Allostasis Notebook]
*[http://www.macses.ucsf.edu/Research/Allostatic/chapters.html John D. and Catherine T. MacArthur Research Network on Socioeconomic Status and Health: Allostatic Load and Allostasis Notebook]
*Table of Contents
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/allostatic.html Allostatic Load and Allostasis]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/antibody.html Antibody Response to an Antigenic Challenge]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/body.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/body.html Body Composition]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/cardiovascular.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/cardiovascular.html Cardiovascular Measures of Allostatic Load]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/catecholamine.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/catecholamine.html Catecholamines and Environmental Stress]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/fat.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/fat.html Central Body Fat]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/cellimmunity.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/cellimmunity.html Decrease in Cell-mediated Immunity - A Marker for Allostatic Load Effects on Immune Function]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/diet.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/diet.html Dietary Factors and SES]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/fibrinogen.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/fibrinogen.html Fibrinogen is a Candidate Measure of Allostatic Load]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/heart.rate.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/heart.rate.html Heart Rate Variability]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/memory.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/memory.html Memory Function and Hippocampal Formation Volume]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/control.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/control.html Modes of Cardiac Control]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/muscle.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/muscle.html Muscle Tension]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/parasym.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/parasym.html Parasympathetic Function]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/salivarycort.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/salivarycort.html Salivary Cortisol Measurement and Challenge Tests]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/sleep.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/sleep.html Sleep Quantity and Endocrine Markers of Sleep Quality]
:*[http://www.macses.ucsf.edu/Research/Allostatic/notebook/vital.htmlhttp://www.macses.ucsf.edu/Research/Allostatic/notebook/vital.html Vital Exhaustion - A Syndrome of Psychological Distress]


:———


Table of Contents
*[http://mcb.berkeley.edu/courses/mcb135k/allostasis.html Allostasis to Maintain Homeostasis: U.C. Berkeley - MCB135k: Physiology of the Aging Process]
:*Wear and tear are caused not only by changes in function but also by repeated fluctuations of various physiological systems and/or long-term exposure to elevated levels of physiological activity.
:*Homeostasis: emphasis is on steady state and optimal set points.
:*Allostasis: emphsis is on optimal operating ranges of physiological systems.
:*Effects of cumulative effects of stress on health and longevity.
:*Allostatic Load: stability through change represents the cumulative, multi-system view of physiological toll that may be exacted on the body through attempts at adaptation.
:*An organism must vary all parameters of its internal milieu and match them appropriately to environmental demands.


1.  Allostatic Load and Allostasis
:———
2.  Antibody Response to an Antigenic Challenge
3.  Body Composition
4.  Cardiovascular Measures of Allostatic Load
5.  Catecholamines and Environmental Stress
6.  Central Body Fat
7.  Decrease in Cell-mediated Immunity - A Marker
        for Allostatic Load Effects on Immune Function
8.  Dietary Factors and SES
9.  Fibrinogen is a Candidate Measure of Allostatic Load
10. Heart Rate Variability
11. Memory Function and Hippocampal Formation Volume
12. Modes of Cardiac Control
13. Muscle Tension
14. Parasympathetic Function
15. Salivary Cortisol Measurement and Challenge Tests
16. Sleep Quantity and Endocrine Markers of Sleep Quality
17. Vital Exhaustion - A Syndrome of Psychological Distress


John D. and Catherine T. MacArthur
*[http://www.rockefeller.edu/labheads/mcewen/intro.php Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology]
Research Network on Socioeconomic Status and Health


working on this...--[[User:Anthony.Sebastian|Anthony.Sebastian]] 23:07, 8 November 2008 (UTC)
:———


 
*[http://johnhawks.net/weblog/topics/energetics/allostasis_mcewen_wingfield_2003.html Allostasis in Human Evolution]
:*John Hawks Weblog: paleoanthropology, genetics, and evolution


:———


*[http://www.ma.uni-heidelberg.de/inst/miph/forschung_psychosozial_en.php Mannheim Institute of Public Health, University of Heidelberg]
:*Psychosocial Risk Factors and Allostatic Load


 
:———
 
Allostatic Load and Allostasis Notebook
 
Table of Contents
 
1.  Allostatic Load and Allostasis
2.  Antibody Response to an Antigenic Challenge
3.  Body Composition
4.  Cardiovascular Measures of Allostatic Load
5.  Catecholamines and Environmental Stress
6.  Central Body Fat
7.  Decrease in Cell-mediated Immunity - A Marker
        for Allostatic Load Effects on Immune Function
8.  Dietary Factors and SES
9.  Fibrinogen is a Candidate Measure of Allostatic Load
10. Heart Rate Variability
11. Memory Function and Hippocampal Formation Volume
12. Modes of Cardiac Control
13. Muscle Tension
14. Parasympathetic Function
15. Salivary Cortisol Measurement and Challenge Tests
16. Sleep Quantity and Endocrine Markers of Sleep Quality
17. Vital Exhaustion - A Syndrome of Psychological Distress
 
*[ Allostatic Load and Allostasis Notebook
 
Table of Contents
 
1.  Allostatic Load and Allostasis
2.  Antibody Response to an Antigenic Challenge
3.  Body Composition
4.  Cardiovascular Measures of Allostatic Load
5.  Catecholamines and Environmental Stress
6.  Central Body Fat
7.  Decrease in Cell-mediated Immunity - A Marker
        for Allostatic Load Effects on Immune Function
8.  Dietary Factors and SES
9.  Fibrinogen is a Candidate Measure of Allostatic Load
10. Heart Rate Variability
11. Memory Function and Hippocampal Formation Volume
12. Modes of Cardiac Control
13. Muscle Tension
14. Parasympathetic Function
15. Salivary Cortisol Measurement and Challenge Tests
16. Sleep Quantity and Endocrine Markers of Sleep Quality
17. Vital Exhaustion - A Syndrome of Psychological Distress

Latest revision as of 16:38, 9 November 2008

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A hand-picked, annotated list of Web resources about Allostasis and allostatic load.
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  • Wear and tear are caused not only by changes in function but also by repeated fluctuations of various physiological systems and/or long-term exposure to elevated levels of physiological activity.
  • Homeostasis: emphasis is on steady state and optimal set points.
  • Allostasis: emphsis is on optimal operating ranges of physiological systems.
  • Effects of cumulative effects of stress on health and longevity.
  • Allostatic Load: stability through change represents the cumulative, multi-system view of physiological toll that may be exacted on the body through attempts at adaptation.
  • An organism must vary all parameters of its internal milieu and match them appropriately to environmental demands.
———
———
  • John Hawks Weblog: paleoanthropology, genetics, and evolution
———
  • Psychosocial Risk Factors and Allostatic Load
———
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