Fluvastatin: Difference between revisions

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[[Image:Fluvastatin structure.jpg|right|thumb|200px|{{#ifexist:Template:Fluvastatin structure.jpg/credit|{{Fluvastatin structure.jpg/credit}}<br/>|}}Fluvastatin, a class II statin.]]
{{Image|Fluvastatin structure.jpg|right|200px|Fluvastatin, a type II statin.}}


'''Fluvastatin''', also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and  fluindostatin, is a class II statin used for the treatment of high cholesterol levels ([[hypercholesterolemia]]), the prevention of [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish [[atherosclerosis|arterial plaque]] formation.  It is used to reduce levels of total cholesterol, LDL-cholesterol, [[triglyceride]]s and apo B.  It was the first synthetically derived [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] and like the other class II statins, [[carivastin]], [[atorvastatin]] and [[rosuvastatin]], it is based on an [[indole]] ring structure rather than the naphthalene ring system present in the class I statins [[mevastatin]], [[lovastatin]], [[pravastatin]] and [[simvastatin]].  Suppression of HMG-CoA reductase decreases production of [[mevalonate]], a key chemical precursor of [[cholesterol]].
'''Fluvastatin''', also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and  fluindostatin, is a type II statin used for the treatment of high cholesterol levels ([[hypercholesterolemia]]), the prevention of [[myocardial infarction|heart attacks]] and [[stroke]]s, and to diminish [[atherosclerosis|arterial plaque]] formation.  It is used to reduce levels of total cholesterol, LDL-cholesterol, [[triglyceride]]s and apo B.  It was the first synthetically derived [[Hydroxymethylglutaryl-coenzyme A reductase inhibitor|HMG-CoA reductase inhibitor]] and like the other type II statins, [[carivastin]], [[atorvastatin]] and [[rosuvastatin]], it is based on an fluorophenyl  structure rather than the naphtha ring system present in the type I statins [[mevastatin]], [[lovastatin]], [[pravastatin]] and [[simvastatin]].  Suppression of HMG-CoA reductase decreases production of [[mevalonate]], a key chemical precursor of [[cholesterol]].


Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>24</sub>H<sub>26</sub>FNO<sub>4</sub>.
Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C<sub>24</sub>H<sub>26</sub>FNO<sub>4</sub>.
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Fluvastatin is sold in the following brand name products.
Fluvastatin is sold in the following brand name products.


*Cranoc
*Cranoc®
*Lescol
*Lescol®
*Lescol XL
*Lescol XL®
*Canef
*Canef®
 
== External links ==
{{CZMed}}[[Category:Suggestion Bot Tag]]

Latest revision as of 12:04, 17 August 2024

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Fluvastatin, a type II statin.

Fluvastatin, also called luvastatina (Spanish) fluvastatine (French), fluvastatinum (Latin) and fluindostatin, is a type II statin used for the treatment of high cholesterol levels (hypercholesterolemia), the prevention of heart attacks and strokes, and to diminish arterial plaque formation. It is used to reduce levels of total cholesterol, LDL-cholesterol, triglycerides and apo B. It was the first synthetically derived HMG-CoA reductase inhibitor and like the other type II statins, carivastin, atorvastatin and rosuvastatin, it is based on an fluorophenyl structure rather than the naphtha ring system present in the type I statins mevastatin, lovastatin, pravastatin and simvastatin. Suppression of HMG-CoA reductase decreases production of mevalonate, a key chemical precursor of cholesterol.

Its official IUPAC chemical name is (E,3S,5R)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C24H26FNO4.

brand names

Fluvastatin is sold in the following brand name products.

  • Cranoc®
  • Lescol®
  • Lescol XL®
  • Canef®

External links

The most up-to-date information about Fluvastatin and other drugs can be found at the following sites.