Talk:Steroid

Naming convention

I could be wrong, but I thought the usual naming convention is to have a singular title. In this case, "Steroid". In this way, the first line would be changed to "A steroid, (or steroid hormone), is a powerful hormone with drastic effects, both good and bad, when artificially introduced into living systems." If figure if a change needs to occur, it should happen before the subpages are created. Richard Pettitt 10:30, 21 December 2007 (CST)

Ttile fixed, thank for the reminder Richard.

Also, I can't decide how much information to put on this page regarding each of the classes of steroids. At present, I think more detailed pages for each steroid, or class of steroids, is needed to detail the physiological role of each group or each particular steroid. David E. Volk 11:43, 21 December 2007 (CST)

Organization

Great start on this page. Can we change organization to something like:

==Classification==

• Corticosteroids
  • Glucocorticoids
  • Mineralcorticoids
• Sex steroids (estrogens and androgens)
• Progestagens

==Biochemistry==

• Synthesis

(put cholesterol section here)

• Mechanism of action

(put hormone receptors and mechanism of action here)

==Medical uses of steroids== (put Cortisone and Prednisone section here)

==Diseases of steroid metabolism==

• 21-hydroxylase deficiency (Congenital Adrenal Hyperplasia)

If this is ok, I am happy to take first attempt at this. - Robert Badgett 23:46, 31 December 2007 (CST)

Robert, I agree with you. I have been wondering if what I have written so far should be a subpage called steroid biosynthesis, are a section. However, I always like to see pictures of things being discussed. The health related topics should dominate the article, with the synthesis as a fill-in. Go ahead and re-write as you see fit and I will come back through the article afterwards. David E. Volk 09:24, 1 January 2008 (CST)

Done, please check some small rewordings I did at 1) from the beginning of Progestagens section I moved a sentence to the Synthesis section, 2) start of sex steroids I reversed a sentence so the links to the more specific articles would be easier to find, 3) I added a few words to the Medical uses section. - Robert Badgett 15:26, 1 January 2008 (CST)

In order for the biochemistry to flow correctly, we should probably start discussing the largest steroids first. Then the biochemistry/structures will flow in an orderly fashion. So probably, in this order

• Progestagens - start of life, pregency
• Corticosteroids - metabolism in general
  • Glucocorticoids
  • Mineralcorticoids
• Sex steroids - sexual dimorphism
  • androgens
  • estrogens

David E. Volk 14:12, 27 March 2008 (CDT)

Approval

I'd like to see this moved swiftly to Approval. I thought it lacked a bit on the history so added a section on the Nobel Prize but that could easily be moved to another article if others differ. I think it would be better for a few lines on HRT and a few lines on Contraceptive use. But basically I'm willing to support swift approval.Gareth Leng 17:15, 14 January 2009 (UTC)

I would second or third approval. In the future I intend to rewrite the chemistry style guide to make our figures color-blind friendly. I like the present color images but we should strive for universal readability. So, we can approve now and change in the images later in drafts. David E. Volk 17:57, 17 January 2009 (UTC)

AIS

Do we want to use AIS as an interesting example of XY humans that can be female? Ir we could leave that in the related articles subpage. Chris Day 17:56, 14 January 2009 (UTC)

Good one! added a line.Gareth Leng 13:46, 17 January 2009 (UTC)