Electronic health record: Difference between revisions

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The electronic health record (EHR) is defined as a "computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record."<ref>{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&term=Computerized+Medical+Records+System |title=MeSH Descriptor Data|author=National Library of Medicine |accessdate=2007-10-23 |format= |work=}}</ref>
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The '''electronic health record''' (EHR) is defined as a "computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record."<ref>{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2007/MB_cgi?mode=&term=Computerized+Medical+Records+System |title=MeSH Descriptor Data|author=National Library of Medicine |accessdate=2007-10-23 |format= |work=}}</ref>


Personal health record (PHR) is a variation in which the patient maintains the data rather than the health care provider maintaining the data.<ref name="pmid17947615">{{cite journal |author=Halamka J, Mandl KD, Tang P |title=Early Experiences with Personal Health Records |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947615 |doi=10.1197/jamia.M2562 |issn=}}</ref><ref> Steinbrook, R. (2008). Personally Controlled Online Health Data -- The Next Big Thing in Medical Care? N Engl J Med, 358(16), 1653-1656. {{DOI|10.1056/NEJMp0801736}}</ref> Examples of PHR include Dossia (http://www.dossia.org) and  Microsoft HealthVault (http://www.healthvault.com).
Personal health record (PHR) is a variation in which the patient maintains the data rather than the health care provider maintaining the data.<ref name="pmid17947615">{{cite journal |author=Halamka J, Mandl KD, Tang P |title=Early Experiences with Personal Health Records |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947615 |doi=10.1197/jamia.M2562 |issn=}}</ref><ref> Steinbrook, R. (2008). Personally Controlled Online Health Data -- The Next Big Thing in Medical Care? N Engl J Med, 358(16), 1653-1656. {{DOI|10.1056/NEJMp0801736}}</ref> Examples of PHR include Dossia (http://www.dossia.org) and  Microsoft HealthVault (http://www.healthvault.com).
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==Features==
==Features==
===Problem lists===
One study noted that less than half of patients with [[splenectomy]] had it recorded in their problem lists. However, "among these patients, the pneumococcal vaccination rate was 17%, as  compared with 54% among patients whose splenectomy was included on the  problem list"<ref>{{cite web |url= http://healthpolicyandreform.nejm.org/?p=15102&query=home |title=Incomplete Care — On the Trail of Flaws in the System &#124; Health Policy and Reform |first= |last=Gandhi |work=healthpolicyandreform.nejm.org |year=2011 [last update] |accessdate=August 10, 2011}}</ref>
Interventions may increase completeness of problem lists.<ref name="pmid22215056">{{cite journal| author=Wright A, Pang J, Feblowitz JC, Maloney FL, Wilcox AR, McLoughlin KS et al.| title=Improving completeness of electronic problem lists through clinical decision support: a randomized, controlled trial. | journal=J Am Med Inform Assoc | year= 2012 | volume=  | issue=  | pages=  | pmid=22215056 | doi=10.1136/amiajnl-2011-000521 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22215056  }} </ref>
===Medical order entry system (CPOE)===
===Medical order entry system (CPOE)===
{{main|Medical order entry system}}
{{main|Medical order entry system}}
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}}</ref>, identifying smoking status of patients<ref name="pmid17947619">{{cite journal |author=Clark C, Good K, Jezierny L, Macpherson M, Wilson B, Chajewska U |title=Identifying Smokers with a Medical Extraction System |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947619 |doi=10.1197/jamia.M2442 |issn=}}</ref><ref name="pmid17947622">{{cite journal |author=Savova GK, Ogren PV, Duffy PH, Buntrock JD, Chute CG |title=Mayo Clinic NLP System for Patient Smoking Status Identification |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947622 |doi=10.1197/jamia.M2437 |issn=}}</ref>, sequences of events<ref name="pmid17947618">{{cite journal |author=Zhou L, Parsons S, Hripcsak G |title=The Evaluation of a Temporal Reasoning System in Processing Clinical Discharge Summaries |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947618 |doi=10.1197/jamia.M2467 |issn=}}</ref>, categorization of physical examination findings<ref name="pmidpendingSerguei">Serguei V.S. Pakhomov et al., “Automatic Classification of Foot Examination Findings using Statistical Natural Language Processing and Machine Learning,” J Am Med Inform Assoc (December 20, 2007), http://www.jamia.org/cgi/content/abstract/M2585v1 (accessed December 21, 2007).</ref> and use of medications for specific diseases.<ref name="pmid17947625">{{cite journal |author=Chen ES, Hripcsak G, Xu H, Markatou M, Friedman C |title=Automated Acquisition of Disease-Drug Knowledge from Biomedical and Clinical Documents: An Initial Study |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947625 |doi=10.1197/jamia.M2401 |issn=}}</ref>
}}</ref>, identifying smoking status of patients<ref name="pmid17947619">{{cite journal |author=Clark C, Good K, Jezierny L, Macpherson M, Wilson B, Chajewska U |title=Identifying Smokers with a Medical Extraction System |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947619 |doi=10.1197/jamia.M2442 |issn=}}</ref><ref name="pmid17947622">{{cite journal |author=Savova GK, Ogren PV, Duffy PH, Buntrock JD, Chute CG |title=Mayo Clinic NLP System for Patient Smoking Status Identification |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947622 |doi=10.1197/jamia.M2437 |issn=}}</ref>, sequences of events<ref name="pmid17947618">{{cite journal |author=Zhou L, Parsons S, Hripcsak G |title=The Evaluation of a Temporal Reasoning System in Processing Clinical Discharge Summaries |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947618 |doi=10.1197/jamia.M2467 |issn=}}</ref>, categorization of physical examination findings<ref name="pmidpendingSerguei">Serguei V.S. Pakhomov et al., “Automatic Classification of Foot Examination Findings using Statistical Natural Language Processing and Machine Learning,” J Am Med Inform Assoc (December 20, 2007), http://www.jamia.org/cgi/content/abstract/M2585v1 (accessed December 21, 2007).</ref> and use of medications for specific diseases.<ref name="pmid17947625">{{cite journal |author=Chen ES, Hripcsak G, Xu H, Markatou M, Friedman C |title=Automated Acquisition of Disease-Drug Knowledge from Biomedical and Clinical Documents: An Initial Study |journal=J Am Med Inform Assoc |volume= |issue= |pages= |year=2007 |pmid=17947625 |doi=10.1197/jamia.M2401 |issn=}}</ref>


In the [[United States]], the [[National Cancer Institute]] has established the [https://cabig-kc.nci.nih.gov/Vocab/KC/index.php/Open_Health_Natural_Language_Processing_%28OHNLP%29_Consortium Open Health Natural Language Processing  Consortium] to promote natural language processing.
In the [[United States of America]], the [[National Cancer Institute]] has established the [https://cabig-kc.nci.nih.gov/Vocab/KC/index.php/Open_Health_Natural_Language_Processing_%28OHNLP%29_Consortium Open Health Natural Language Processing  Consortium] to promote natural language processing.


===Interoperability===
===Interoperability===
Ideally, patient data should be able to be transferred across different EHRs as patients move across health care systems. Networked EHRs are call to a health information exchange (HIE) or regional health information organization (RHIO).
Ideally, patient data should be able to be transferred across different EHRs as patients move across health care systems. Networked EHRs are call to a health information exchange (HIE) or regional health information organization (RHIO).


In 1999 the Santa Barbara County Care Data Exchange was initially funded by $10 million dollars from the California HealthCare Foundation in order to be HIE demonstration project.<ref name="pmid17670775">{{cite journal |author=Miller RH, Miller BS |title=The Santa Barbara County Care Data Exchange: what happened? |journal=Health affairs (Project Hope) |volume=26 |issue=5 |pages=w568–80 |year=2007 |pmid=17670775 |doi=10.1377/hlthaff.26.5.w568}}</ref> By fall 2006, two organizations within the HIE were able to exchange some information. However, in December 2006 the project's board decided to close the project due to funding problems.
In 1999 the Santa Barbara County Care Data Exchange was initially funded by $10 million dollars from the California HealthCare Foundation in order to be HIE demonstration project.<ref name="pmid17670775"/> By fall 2006, two organizations within the HIE were able to exchange some information. However, in December 2006 the project's board decided to close the project due to funding problems.


Other RHIOs include The [http://www.regenstrief.org/medinformatics/inpc Indiana network for patient care] (INPC)<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Indiana&Record=247 |author=Foundation for eHealth Initiative|title=Indiana Health Information Exchange (Indiana Health Information Exchange) |accessdate=2007-11-01 |format= |work=}}</ref><ref name="pmid17911765">{{cite journal |author=Zafar A, Dixon BE |title=Pulling back the covers: technical lessons of a real-world health information exchange |journal=Medinfo |volume=12 |issue=Pt 1 |pages=488–92 |year=2007 |pmid=17911765 |doi= |issn=}}</ref><ref name="pmid16162565">{{cite journal |author=McDonald CJ, Overhage JM, Barnes M, ''et al'' |title=The Indiana network for patient care: a working local health information infrastructure. An example of a working infrastructure collaboration that links data from five health systems and hundreds of millions of entries |journal=Health affairs (Project Hope) |volume=24 |issue=5 |pages=1214–20 |year=2005 |pmid=16162565 |doi=10.1377/hlthaff.24.5.1214}}</ref>, the [http://www.maehc.org/ Massachusetts eHealth Collaborative] (MAeHC)<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Massachusetts&Record=314 |title=Massachusetts eHealth Collaborative (Massachusetts eHealth Collaborative)|author=Foundation for eHealth Initiative |accessdate=2007-11-01 |format= |work=}}</ref> funded by $50 million dollars from Blue Cross Blue Shield of Massachusetts<ref>{{cite web |url=http://www.maehc.org/aboutUs_missionStatement.html |title=About Us - Mission Statement|author=Massachusetts eHealth Collaborative |accessdate=2007-11-01 |format= |work=}}</ref>, and Inland Northwest Health Services (Spokane).<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Washington&Record=297 |title=Inland Northwest Health Services(Inland Northwest Health Services)|author=Foundation for eHealth Initiative  |accessdate=2007-11-01 |format= |work=}}</ref>
Other RHIOs include The [http://www.regenstrief.org/medinformatics/inpc Indiana network for patient care] (INPC)<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Indiana&Record=247 |author=Foundation for eHealth Initiative|title=Indiana Health Information Exchange (Indiana Health Information Exchange) |accessdate=2007-11-01 |format= |work=}}</ref><ref name="pmid17911765">{{cite journal |author=Zafar A, Dixon BE |title=Pulling back the covers: technical lessons of a real-world health information exchange |journal=Medinfo |volume=12 |issue=Pt 1 |pages=488–92 |year=2007 |pmid=17911765 |doi= |issn=}}</ref><ref name="pmid16162565">{{cite journal |author=McDonald CJ, Overhage JM, Barnes M, ''et al'' |title=The Indiana network for patient care: a working local health information infrastructure. An example of a working infrastructure collaboration that links data from five health systems and hundreds of millions of entries |journal=Health affairs (Project Hope) |volume=24 |issue=5 |pages=1214–20 |year=2005 |pmid=16162565 |doi=10.1377/hlthaff.24.5.1214}}</ref>, the [http://www.maehc.org/ Massachusetts eHealth Collaborative] (MAeHC)<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Massachusetts&Record=314 |title=Massachusetts eHealth Collaborative (Massachusetts eHealth Collaborative)|author=Foundation for eHealth Initiative |accessdate=2007-11-01 |format= |work=}}</ref> funded by $50 million dollars from Blue Cross Blue Shield of Massachusetts<ref>{{cite web |url=http://www.maehc.org/aboutUs_missionStatement.html |title=About Us - Mission Statement|author=Massachusetts eHealth Collaborative |accessdate=2007-11-01 |format= |work=}}</ref>, and Inland Northwest Health Services (Spokane).<ref>{{cite web |url=http://ccbh.ehealthinitiative.org/communities/states.aspx?Location=Washington&Record=297 |title=Inland Northwest Health Services(Inland Northwest Health Services)|author=Foundation for eHealth Initiative  |accessdate=2007-11-01 |format= |work=}}</ref>


In the [[United States]], the Department of Veteran Affairs and the Department of Defense are creating data exchange between their EHRs.<ref> Bouhaddou, O., Warnekar, P., Parrish, F., Do, N., Mandel, J., Kilbourne, J., et al. (2008). [http://www.jamia.org/cgi/content/full/15/2/174 Exchange of computable patient data between the department of veterans affairs (VA) and the department of defense (DOD): terminology mediation strategy], J Am Med Inform Assoc, 15(2), 174-183. doi: 10.1197/jamia.M2498.
In the [[United States of America]], the Department of Veteran Affairs and the Department of Defense are creating data exchange between their EHRs.<ref> Bouhaddou, O., Warnekar, P., Parrish, F., Do, N., Mandel, J., Kilbourne, J., et al. (2008). [http://www.jamia.org/cgi/content/full/15/2/174 Exchange of computable patient data between the department of veterans affairs (VA) and the department of defense (DOD): terminology mediation strategy], J Am Med Inform Assoc, 15(2), 174-183. doi: 10.1197/jamia.M2498.


</ref>
</ref>
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===Clinical care===
===Clinical care===
====Unintended consequences====
====Unintended consequences====
Unintended consequences, that are a mix of positive and negative, may occur to [[computerized provider order entry]].<ref name="pmid17460127">{{cite journal |author=Ash JS, Sittig DF, Poon EG, Guappone K, Campbell E, Dykstra RH |title=The extent and importance of unintended consequences related to computerized provider order entry |journal=J Am Med Inform Assoc |volume=14 |issue=4 |pages=415–23 |year=2007 |pmid=17460127 |doi=10.1197/jamia.M2373}}</ref>
Unintended consequences, that are a mix of positive and negative, may occur to [[Medical order entry system|computerized provider order entry]].<ref name="pmid17460127">{{cite journal |author=Ash JS, Sittig DF, Poon EG, Guappone K, Campbell E, Dykstra RH |title=The extent and importance of unintended consequences related to computerized provider order entry |journal=J Am Med Inform Assoc |volume=14 |issue=4 |pages=415–23 |year=2007 |pmid=17460127 |doi=10.1197/jamia.M2373}}</ref>


=====Adverse effects=====
=====Adverse effects=====
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Implementation of the computerized provider order entry has been associated with medication errors<ref name="pmid15755942">{{cite journal |author=Koppel R, Metlay JP, Cohen A, ''et al'' |title=Role of computerized physician order entry systems in facilitating medication errors |journal=JAMA |volume=293 |issue=10 |pages=1197–203 |year=2005 |pmid=15755942 |doi=10.1001/jama.293.10.1197}}</ref> This may be due to computer interfaces that are not intuitive to use.<ref>{{cite web |url=http://www.useit.com/alertbox/20050411.html |title=Medical Usability: How to Kill Patients Through Bad Design (Jakob Nielsen's Alertbox) |accessdate=2007-10-23 |author=Nielsen, Jakob |authorlink= |coauthors= |date=April 11, 2005 |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote=}}</ref>
Implementation of the computerized provider order entry has been associated with medication errors<ref name="pmid15755942">{{cite journal |author=Koppel R, Metlay JP, Cohen A, ''et al'' |title=Role of computerized physician order entry systems in facilitating medication errors |journal=JAMA |volume=293 |issue=10 |pages=1197–203 |year=2005 |pmid=15755942 |doi=10.1001/jama.293.10.1197}}</ref> This may be due to computer interfaces that are not intuitive to use.<ref>{{cite web |url=http://www.useit.com/alertbox/20050411.html |title=Medical Usability: How to Kill Patients Through Bad Design (Jakob Nielsen's Alertbox) |accessdate=2007-10-23 |author=Nielsen, Jakob |authorlink= |coauthors= |date=April 11, 2005 |format= |work= |publisher= |pages= |language= |archiveurl= |archivedate= |quote=}}</ref>


Computerized provider order entry has been associated with causing a number of unintended consequences with "new work/more work, workflow, system demands, communication, emotions, and dependence on the technology" being most severe.<ref name="pmid17460127">{{cite journal |author=Ash JS, Sittig DF, Poon EG, Guappone K, Campbell E, Dykstra RH |title=The extent and importance of unintended consequences related to computerized provider order entry |journal=Journal of the American Medical Informatics Association : JAMIA |volume=14 |issue=4 |pages=415–23 |year=2007 |pmid=17460127 |doi=10.1197/jamia.M2373}}</ref> In this study, shifts in power ("The presence of a system that enforces specific clinical practices through mandatory data entry fields changes the power structure of organizations. Often the power or autonomy of physicians is reduced, while the power of the nursing staff, information technology specialists, and administration is increased") were also observed.
Computerized provider order entry has been associated with causing a number of unintended consequences with "new work/more work, workflow, system demands, communication, emotions, and dependence on the technology" being most severe.<ref name="pmid17460127"/> In this study, shifts in power ("The presence of a system that enforces specific clinical practices through mandatory data entry fields changes the power structure of organizations. Often the power or autonomy of physicians is reduced, while the power of the nursing staff, information technology specialists, and administration is increased") were also observed.


The introduction of computerized provider order entry has been associated with increased hospital mortality in some<ref name="pmid16322178">{{cite journal |author=Han YY, Carcillo JA, Venkataraman ST, ''et al'' |title=Unexpected increased mortality after implementation of a commercially sold computerized physician order entry system |journal=Pediatrics |volume=116 |issue=6 |pages=1506–12 |year=2005 |pmid=16322178 |doi=10.1542/peds.2005-1287}}</ref>, but not all studies.<ref name="pmid17417119">{{cite journal |author=Keene A, Ashton L, Shure D, Napoleone D, Katyal C, Bellin E |title=Mortality before and after initiation of a computerized physician order entry system in a critically ill pediatric population |journal=Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies |volume=8 |issue=3 |pages=268–71 |year=2007 |pmid=17417119 |doi=10.1097/01.PCC.0000260781.78277.D9}}</ref><ref name="pmid16818577">{{cite journal |author=Del Beccaro MA, Jeffries HE, Eisenberg MA, Harry ED |title=Computerized provider order entry implementation: no association with increased mortality rates in an intensive care unit |journal=Pediatrics |volume=118 |issue=1 |pages=290–5 |year=2006 |pmid=16818577 |doi=10.1542/peds.2006-0367}}</ref>
The introduction of computerized provider order entry has been associated with increased hospital mortality in some<ref name="pmid16322178">{{cite journal |author=Han YY, Carcillo JA, Venkataraman ST, ''et al'' |title=Unexpected increased mortality after implementation of a commercially sold computerized physician order entry system |journal=Pediatrics |volume=116 |issue=6 |pages=1506–12 |year=2005 |pmid=16322178 |doi=10.1542/peds.2005-1287}}</ref>, but not all studies.<ref name="pmid17417119">{{cite journal |author=Keene A, Ashton L, Shure D, Napoleone D, Katyal C, Bellin E |title=Mortality before and after initiation of a computerized physician order entry system in a critically ill pediatric population |journal=Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies |volume=8 |issue=3 |pages=268–71 |year=2007 |pmid=17417119 |doi=10.1097/01.PCC.0000260781.78277.D9}}</ref><ref name="pmid16818577">{{cite journal |author=Del Beccaro MA, Jeffries HE, Eisenberg MA, Harry ED |title=Computerized provider order entry implementation: no association with increased mortality rates in an intensive care unit |journal=Pediatrics |volume=118 |issue=1 |pages=290–5 |year=2006 |pmid=16818577 |doi=10.1542/peds.2006-0367}}</ref>
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===Quality management===
===Quality management===
There have been very few studies assessing the quality content [http://compete-study.com/documents/Data_Quality_Management_and_EMR_Entry_%5BPowerPoint_presentation%5D.pdf].
There have been very few studies assessing the quality content [http://compete-study.com/documents/Data_Quality_Management_and_EMR_Entry_%5BPowerPoint_presentation%5D.pdf].
====Standards====
There are some international efforts going on to ensure that standards are followed.
Common Standards are:
* [[HL7]] [http://www.hl7.org/index.cfm]
* [[openEHR]] [http://www.openehr.org/home.html]
* [[CDISC]] [http://www.cdisc.org/]
* [[IHE]] [http://www.ihe.net/]
* [[ISO TC 215]] [http://www.iso.org/iso/iso_technical_committee?commid=54960]


===Rapid system learning===
===Rapid system learning===
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}}</ref><ref name="pmid19171805">{{cite journal |author=Amarasingham R, Plantinga L, Diener-West M, Gaskin DJ, Powe NR |title=Clinical information technologies and inpatient outcomes: a multiple hospital study |journal=Arch. Intern. Med. |volume=169 |issue=2 |pages=108–14 |year=2009 |month=January |pmid=19171805 |doi=10.1001/archinternmed.2008.520 |url=http://archinte.ama-assn.org/cgi/pmidlookup?view=long&pmid=19171805 |issn=}}</ref>
}}</ref><ref name="pmid19171805">{{cite journal |author=Amarasingham R, Plantinga L, Diener-West M, Gaskin DJ, Powe NR |title=Clinical information technologies and inpatient outcomes: a multiple hospital study |journal=Arch. Intern. Med. |volume=169 |issue=2 |pages=108–14 |year=2009 |month=January |pmid=19171805 |doi=10.1001/archinternmed.2008.520 |url=http://archinte.ama-assn.org/cgi/pmidlookup?view=long&pmid=19171805 |issn=}}</ref>


Physicians with complete an electronic health record tend to better follow-up on abnormal [[diagnostic test]]s.<ref>{{Cite journal
Physicians with complete an electronic health record tend to better follow-up on abnormal [[diagnostic test]]s<ref>{{Cite journal
| doi = 10.1001/archinternmed.2009.130
| doi = 10.1001/archinternmed.2009.130
| volume = 169
| volume = 169
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| date = 2009-06-22
| date = 2009-06-22
| url = http://archinte.ama-assn.org/cgi/content/abstract/169/12/1123
| url = http://archinte.ama-assn.org/cgi/content/abstract/169/12/1123
}}</ref>
}}</ref> and perform higher on HEDIS measures.<ref name="pmid19805769">{{cite journal| author=Friedberg MW, Coltin KL, Safran DG, Dresser M, Zaslavsky AM, Schneider EC| title=Associations between structural capabilities of primary care practices and performance on selected quality measures. | journal=Ann Intern Med | year= 2009 | volume= 151 | issue= 7 | pages= 456-63 | pmid=19805769
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19805769 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>
 
Kaiser Permanente found that implementing an EHR was associated with a reduction in office visits as clinical interactions shifted to new methods such as email.<ref name="pmid19687504">{{cite journal| author=Wilson JF| title=Making electronic health records meaningful. | journal=Ann Intern Med | year= 2009 | volume= 151 | issue= 4 | pages= 293-6 | pmid=19687504
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=clinical.uthscsa.edu/cite&email=badgett@uthscdsa.edu&retmode=ref&cmd=prlinks&id=19687504 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>


==Implementation==
==Implementation==
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====Successful implementations====
====Successful implementations====
The [[United States]] Department of Veterans Affairs has successfully implemented an electronic health record system, "''VistA''", across a very large health care system.<ref name="pmid12810119">{{cite journal |author=Brown SH, Lincoln MJ, Groen PJ, Kolodner RM |title=VistA--U.S. Department of Veterans Affairs national-scale HIS |journal=International journal of medical informatics |volume=69 |issue=2-3 |pages=135–56 |year=2003 |pmid=12810119 |doi= |issn=}}</ref><ref name="pmid11309758">{{cite journal |author=Fletcher RD, Dayhoff RE, Wu CM, Graves A, Jones RE |title=Computerized medical records in the Department of Veterans Affairs |journal=Cancer |volume=91 |issue=8 Suppl |pages=1603–6 |year=2001 |pmid=11309758 |doi= |issn=}}</ref> Although it has been an early innovator, this system occasionally has problems.<ref>{{Cite journal
The [[United States of America]] Department of Veterans Affairs has successfully implemented an electronic health record system, "''VistA''", across a very large health care system.<ref name="pmid12810119">{{cite journal |author=Brown SH, Lincoln MJ, Groen PJ, Kolodner RM |title=VistA--U.S. Department of Veterans Affairs national-scale HIS |journal=International journal of medical informatics |volume=69 |issue=2-3 |pages=135–56 |year=2003 |pmid=12810119 |doi= |issn=}}</ref><ref name="pmid11309758">{{cite journal |author=Fletcher RD, Dayhoff RE, Wu CM, Graves A, Jones RE |title=Computerized medical records in the Department of Veterans Affairs |journal=Cancer |volume=91 |issue=8 Suppl |pages=1603–6 |year=2001 |pmid=11309758 |doi= |issn=}}</ref> Although it has been an early innovator, this system occasionally has problems.<ref>{{Cite journal| doi = 10.1001/jama.2009.239 | volume = 301 | issue = 9
| doi = 10.1001/jama.2009.239
| pages = 919-920 | last = Kuehn | first = Bridget M. | title = IT Vulnerabilities Highlighted by Errors, Malfunctions at Veterans' Medical Centers | journal = JAMA | accessdate = 2009-03-04
| volume = 301
| date = 2009-03-04 | url = http://jama.ama-assn.org }}</ref> VISTA has been promoted for use outside of the VA system by groups such as [http://worldvista.org/ WorldVistA].
| issue = 9
| pages = 919-920
| last = Kuehn
| first = Bridget M.
| title = IT Vulnerabilities Highlighted by Errors, Malfunctions at Veterans' Medical Centers
| journal = JAMA
| accessdate = 2009-03-04
| date = 2009-03-04
| url = http://jama.ama-assn.org
}}</ref>


====Unsuccessful implementations====
====Unsuccessful implementations====
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===Outpatient===
===Outpatient===
As of 2008, few clinics in the Untied States had adopted EHRs.<ref name="pmid18565855">{{cite journal| author=DesRoches CM, Campbell EG, Rao SR, Donelan K, Ferris TG, Jha A et al.| title=Electronic health records in ambulatory care--a national survey of physicians. | journal=N Engl J Med | year= 2008 | volume= 359 | issue= 1 | pages= 50-60 | pmid=18565855  
As of 2008, few clinics in the United States had adopted EHRs.<ref name="pmid18565855">{{cite journal| author=DesRoches CM, Campbell EG, Rao SR, Donelan K, Ferris TG, Jha A et al.| title=Electronic health records in ambulatory care--a national survey of physicians. | journal=N Engl J Med | year= 2008 | volume= 359 | issue= 1 | pages= 50-60 | pmid=18565855  
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=18565855 | doi=10.1056/NEJMsa0802005 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=18565855 | doi=10.1056/NEJMsa0802005 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>


EHRs in the outpatient are estimated to provide $86,000 net revenue in 2002 United States dollars which includes an initial cost of $13,100 per provider and a loss during the first year of $8200 per provider.<ref name="pmid12714130">{{cite journal |author=Wang SJ, Middleton B, Prosser LA, ''et al'' |title=A cost-benefit analysis of electronic medical records in primary care |journal=Am. J. Med. |volume=114 |issue=5 |pages=397–403 |year=2003 |pmid=12714130 |doi= |issn=}}</ref> EHRs cost about $15,000 per privider in 2002 American dollars.
EHRs in the outpatient are estimated to provide $86,000 net revenue in 2002 United States dollars which includes an initial cost of $13,100 per provider and a loss during the first year of $8200 per provider.<ref name="pmid12714130"/> EHRs cost about $15,000 per privider in 2002 American dollars.


A [[case study]] describes barriers to implementing an EHR in a private clinic in the [[United States]].<ref name="pmid16061920">{{cite journal| author=Baron RJ, Fabens EL, Schiffman M, Wolf E| title=Electronic health records: just around the corner? Or over the cliff? | journal=Ann Intern Med | year= 2005 | volume= 143 | issue= 3 | pages= 222-6 | pmid=16061920  
A [[case study]] describes barriers to implementing an EHR in a private clinic in the [[United States of America]].<ref name="pmid16061920">{{cite journal| author=Baron RJ, Fabens EL, Schiffman M, Wolf E| title=Electronic health records: just around the corner? Or over the cliff? | journal=Ann Intern Med | year= 2005 | volume= 143 | issue= 3 | pages= 222-6 | pmid=16061920  
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16061920 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>
| url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16061920 }} <!--Formatted by http://sumsearch.uthscsa.edu/cite/--></ref>


Line 142: Line 150:


===Incentives===
===Incentives===
In the [[United States]], the [[Department of Health and Human Services]] and the [[Centers for Medicare and Medicaid Services]] (CMS), have created financial incentives to encourage the adoption of EHRs by [[health care provider]]s and [[hospital]]s who are engaged in "meaningful use of certified electronic health records (EHR) technology".<ref>[http://www.cms.hhs.gov/apps/media/press/factsheet.asp?Counter=3564 Details for: CMS PROPOSES DEFINITION OF MEANINGFUL USE OF CERTIFIED ELECTRONIC HEALTH RECORDS (EHR) TECHNOLOGY] Department of Health and Human Services</ref><ref>[http://www.regulations.gov/search/Regs/home.html#documentDetail?R=0900006480a7c4a8 Proposed Rules] Regulations.gov</ref> The ability of the [[Centers for Medicare and Medicaid Services]] to implement these incentives has been questions.<ref>Kibbe DC. (2010) [http://www.aafp.org/online/en/home/publications/journals/fpm/preprint/ehrincentive.html Should Doctors Reject the Government's EHR Incentive Plan?]</ref>
In the [[United States of America]], the [[Department of Health and Human Services]] and the [[Centers for Medicare and Medicaid Services]] (CMS), have created financial incentives to encourage the adoption of EHRs by [[health care provider]]s and [[hospital]]s who are engaged in "meaningful use of certified electronic health records (EHR) technology".<ref>[http://www.cms.hhs.gov/apps/media/press/factsheet.asp?Counter=3564 Details for: CMS PROPOSES DEFINITION OF MEANINGFUL USE OF CERTIFIED ELECTRONIC HEALTH RECORDS (EHR) TECHNOLOGY] Department of Health and Human Services</ref><ref>[http://www.regulations.gov/search/Regs/home.html#documentDetail?R=0900006480a7c4a8 Proposed Rules] Regulations.gov</ref> This is mandated by the HITECH Act.<ref>{{Cite journal
| doi = 10.1001/jama.2010.1497
| volume = 304
| issue = 15
| pages = 1709-1710
| last = Jha
| first = Ashish K.
| title = Meaningful Use of Electronic Health Records: The Road Ahead
| journal = JAMA
| accessdate = 2010-10-21
| date = 2010-10-20
| url = http://jama.ama-assn.org
}}</ref><ref name="pmid19687504"/> The ability of the [[Centers for Medicare and Medicaid Services]] to implement these incentives has been questions.<ref>Kibbe DC. (2010) [http://www.aafp.org/online/en/home/publications/journals/fpm/preprint/ehrincentive.html Should Doctors Reject the Government's EHR Incentive Plan?]</ref>


==Privacy==
==Privacy==
Line 148: Line 168:


==References==
==References==
<references/>
<small>
<references>


==See also==
</references>
*[[Clinical decision support system]]
</small>
*[[Electronic medical record]]


==External links==
[[Category:Suggestion Bot Tag]]
* [http://ahrq.gov Agency for Healthcare Research and Quality] (AHRQ):  [http://healthit.ahrq.gov/portal/server.pt?open=512&objID=654&&PageID=5984&mode=2&cached=true Health Information Technology Costs & Benefits Database Project]
* [http://www.leapfroggroup.org/ Leapfrog Group]

Latest revision as of 14:03, 5 October 2024

This article is developing and not approved.
Main Article
Discussion
Related Articles  [?]
Bibliography  [?]
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Citable Version  [?]
 
This editable Main Article is under development and subject to a disclaimer.

The electronic health record (EHR) is defined as a "computer-based systems for input, storage, display, retrieval, and printing of information contained in a patient's medical record."[1]

Personal health record (PHR) is a variation in which the patient maintains the data rather than the health care provider maintaining the data.[2][3] Examples of PHR include Dossia (http://www.dossia.org) and Microsoft HealthVault (http://www.healthvault.com).

In the future it is hoped that EHRs across different health care systems will be able to exchange patient information in regional health information organizations (RHIOs); however, this goal has been elusive.[4]

EHRs in the outpatient setting hopefully save costs after an initial period of cost loss.[5] EHRs cost about $15,000 per privider in 2002 American dollars.

Features

Problem lists

One study noted that less than half of patients with splenectomy had it recorded in their problem lists. However, "among these patients, the pneumococcal vaccination rate was 17%, as compared with 54% among patients whose splenectomy was included on the problem list"[6]

Interventions may increase completeness of problem lists.[7]

Medical order entry system (CPOE)

For more information, see: Medical order entry system.

Medical order entry systems, also called computerized provider order entry systems (CPOE) are "information systems, usually computer-assisted, that enable providers to initiate medical procedures, prescribe medications, etc. These systems support medical decision-making and error-reduction during patient care."[8]

Clinical decision support

For more information, see: Clinical decision support system.

Links to medical knowledge

For more information, see: information retrieval.

Content in the EHR that is codifiable with a standard taxonomy can be linked to medical knowledge that is indexed with the same taxonomy. As example is Infobuttons that automatically displays links from the EHR to external knowledge sources.[9] One trial studied the effects of adding a feature to the EHR that allows the clinical to request assistance with information retrieval from an informationist.[10]

Natural language processing

Computers can use text mining to analyze text to in order to create structured data. Attempts at text mining include identifying section headers in clinical notes[11], identifying smoking status of patients[12][13], sequences of events[14], categorization of physical examination findings[15] and use of medications for specific diseases.[16]

In the United States of America, the National Cancer Institute has established the Open Health Natural Language Processing Consortium to promote natural language processing.

Interoperability

Ideally, patient data should be able to be transferred across different EHRs as patients move across health care systems. Networked EHRs are call to a health information exchange (HIE) or regional health information organization (RHIO).

In 1999 the Santa Barbara County Care Data Exchange was initially funded by $10 million dollars from the California HealthCare Foundation in order to be HIE demonstration project.[4] By fall 2006, two organizations within the HIE were able to exchange some information. However, in December 2006 the project's board decided to close the project due to funding problems.

Other RHIOs include The Indiana network for patient care (INPC)[17][18][19], the Massachusetts eHealth Collaborative (MAeHC)[20] funded by $50 million dollars from Blue Cross Blue Shield of Massachusetts[21], and Inland Northwest Health Services (Spokane).[22]

In the United States of America, the Department of Veteran Affairs and the Department of Defense are creating data exchange between their EHRs.[23]

Uses

Clinical care

Unintended consequences

Unintended consequences, that are a mix of positive and negative, may occur to computerized provider order entry.[24]

Adverse effects

Most all of the adverse effects are due to just the computerized provider order entry component of the electronic medical record.

Implementation of the computerized provider order entry has been associated with medication errors[25] This may be due to computer interfaces that are not intuitive to use.[26]

Computerized provider order entry has been associated with causing a number of unintended consequences with "new work/more work, workflow, system demands, communication, emotions, and dependence on the technology" being most severe.[24] In this study, shifts in power ("The presence of a system that enforces specific clinical practices through mandatory data entry fields changes the power structure of organizations. Often the power or autonomy of physicians is reduced, while the power of the nursing staff, information technology specialists, and administration is increased") were also observed.

The introduction of computerized provider order entry has been associated with increased hospital mortality in some[27], but not all studies.[28][29]

Copy and pasting of notes

Copying and pasting of text from an older note to a newer note is common and may lead to incorrect information.[30]

Quality management

There have been very few studies assessing the quality content [1].

Standards

There are some international efforts going on to ensure that standards are followed. Common Standards are:

Rapid system learning

The electronic health record may allow rapid system learning for events such as disease outbreaks.[31]

Research

The electronic health record can provide data for health research. One issue is protecting the privacy of patients.[32][33]. It may also be used for creating a clinical data warehouse.

Benefits

Hospitals with high use of information technology may provide better health care.[34][35]

Physicians with complete an electronic health record tend to better follow-up on abnormal diagnostic tests[36] and perform higher on HEDIS measures.[37]

Kaiser Permanente found that implementing an EHR was associated with a reduction in office visits as clinical interactions shifted to new methods such as email.[38]

Implementation

Inpatient

As of 2008, few a minority of hospitals have adopted EHRs in the United States.[39]

Successful implementations

The United States of America Department of Veterans Affairs has successfully implemented an electronic health record system, "VistA", across a very large health care system.[40][41] Although it has been an early innovator, this system occasionally has problems.[42] VISTA has been promoted for use outside of the VA system by groups such as WorldVistA.

Unsuccessful implementations

  • Kaiser - Hawaii[43]
  • Limpopo (Northern) Province, South Africa[44]

Outpatient

As of 2008, few clinics in the United States had adopted EHRs.[45]

EHRs in the outpatient are estimated to provide $86,000 net revenue in 2002 United States dollars which includes an initial cost of $13,100 per provider and a loss during the first year of $8200 per provider.[5] EHRs cost about $15,000 per privider in 2002 American dollars.

A case study describes barriers to implementing an EHR in a private clinic in the United States of America.[46]

While EHRs may allow doctors to conduct quality improve, the process is difficult.[47]

Incentives

In the United States of America, the Department of Health and Human Services and the Centers for Medicare and Medicaid Services (CMS), have created financial incentives to encourage the adoption of EHRs by health care providers and hospitals who are engaged in "meaningful use of certified electronic health records (EHR) technology".[48][49] This is mandated by the HITECH Act.[50][38] The ability of the Centers for Medicare and Medicaid Services to implement these incentives has been questions.[51]

Privacy

Maintaining privacy of personal health information (PHI) is important goal of the Health Insurance Portability and Accountability Act (HIPAA). Various attempts at automated the de-identification of records are ongoing.[52]

References

  1. National Library of Medicine. MeSH Descriptor Data. Retrieved on 2007-10-23.
  2. Halamka J, Mandl KD, Tang P (2007). "Early Experiences with Personal Health Records". J Am Med Inform Assoc. DOI:10.1197/jamia.M2562. PMID 17947615. Research Blogging.
  3. Steinbrook, R. (2008). Personally Controlled Online Health Data -- The Next Big Thing in Medical Care? N Engl J Med, 358(16), 1653-1656. Template:DOI
  4. 4.0 4.1 Miller RH, Miller BS (2007). "The Santa Barbara County Care Data Exchange: what happened?". Health affairs (Project Hope) 26 (5): w568–80. DOI:10.1377/hlthaff.26.5.w568. PMID 17670775. Research Blogging.
  5. 5.0 5.1 Wang SJ, Middleton B, Prosser LA, et al (2003). "A cost-benefit analysis of electronic medical records in primary care". Am. J. Med. 114 (5): 397–403. DOI:10.1016/S0002-9343(03)00057-3. PMID 12714130. Research Blogging.
  6. Gandhi (2011 [last update]). Incomplete Care — On the Trail of Flaws in the System | Health Policy and Reform. healthpolicyandreform.nejm.org. Retrieved on August 10, 2011.
  7. Wright A, Pang J, Feblowitz JC, Maloney FL, Wilcox AR, McLoughlin KS et al. (2012). "Improving completeness of electronic problem lists through clinical decision support: a randomized, controlled trial.". J Am Med Inform Assoc. DOI:10.1136/amiajnl-2011-000521. PMID 22215056. Research Blogging.
  8. Anonymous (2024), Medical order entry systems (English). Medical Subject Headings. U.S. National Library of Medicine.
  9. Cimino JJ (2006). "Use, usability, usefulness, and impact of an infobutton manager". AMIA Annu Symp Proc: 151–5. PMID 17238321[e] Full text at PubMed Central
  10. Jerome RN, Giuse NB, Rosenbloom ST, Arbogast PG (2008). "Exploring clinician adoption of a novel evidence request feature in an electronic medical record system". J Med Libr Assoc 96 (1): 34–41. DOI:10.3163/1536-5050.96.1.34. PMID 18219379. Research Blogging.
  11. Denny, Joshua C.; Anderson Spickard, Kevin B. Johnson, Neeraja B. Peterson, Josh F. Peterson, Randolph A. Miller (2009-11-01). "Evaluation of a Method to Identify and Categorize Section Headers in Clinical Documents". J Am Med Inform Assoc 16 (6): 806-815. DOI:10.1197/jamia.M3037. Retrieved on 2009-11-10. Research Blogging.
  12. Clark C, Good K, Jezierny L, Macpherson M, Wilson B, Chajewska U (2007). "Identifying Smokers with a Medical Extraction System". J Am Med Inform Assoc. DOI:10.1197/jamia.M2442. PMID 17947619. Research Blogging.
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  21. Massachusetts eHealth Collaborative. About Us - Mission Statement. Retrieved on 2007-11-01.
  22. Foundation for eHealth Initiative. Inland Northwest Health Services(Inland Northwest Health Services). Retrieved on 2007-11-01.
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  27. Han YY, Carcillo JA, Venkataraman ST, et al (2005). "Unexpected increased mortality after implementation of a commercially sold computerized physician order entry system". Pediatrics 116 (6): 1506–12. DOI:10.1542/peds.2005-1287. PMID 16322178. Research Blogging.
  28. Keene A, Ashton L, Shure D, Napoleone D, Katyal C, Bellin E (2007). "Mortality before and after initiation of a computerized physician order entry system in a critically ill pediatric population". Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 8 (3): 268–71. DOI:10.1097/01.PCC.0000260781.78277.D9. PMID 17417119. Research Blogging.
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  31. Reis BY, Kirby C, Hadden LE, et al (2007). "AEGIS: a robust and scalable real-time public health surveillance system". Journal of the American Medical Informatics Association : JAMIA 14 (5): 581–8. DOI:10.1197/jamia.M2342. PMID 17600100. Research Blogging.
  32. Uzuner O, Luo Y, Szolovits P (2007). "Evaluating the state-of-the-art in automatic de-identification". Journal of the American Medical Informatics Association : JAMIA 14 (5): 550–63. DOI:10.1197/jamia.M2444. PMID 17600094. Research Blogging.
  33. Szarvas G, Farkas R, Busa-Fekete R (2007). "State-of-the-art anonymization of medical records using an iterative machine learning framework". Journal of the American Medical Informatics Association : JAMIA 14 (5): 574–80. DOI:10.1197/j.jamia.M2441. PMID 17823086. Research Blogging.
  34. Amarasingham, Ruben; Laura Plantinga, Marie Diener-West, Darrell J. Gaskin, Neil R. Powe (2009-01-26). "Clinical Information Technologies and Inpatient Outcomes: A Multiple Hospital Study". Arch Intern Med 169 (2): 108-114. DOI:10.1001/archinternmed.2008.520. Retrieved on 2009-01-27. Research Blogging.
  35. Amarasingham R, Plantinga L, Diener-West M, Gaskin DJ, Powe NR (January 2009). "Clinical information technologies and inpatient outcomes: a multiple hospital study". Arch. Intern. Med. 169 (2): 108–14. DOI:10.1001/archinternmed.2008.520. PMID 19171805. Research Blogging.
  36. Casalino, Lawrence P.; Daniel Dunham, Marshall H. Chin, Rebecca Bielang, Emily O. Kistner, Theodore G. Karrison, Michael K. Ong, Urmimala Sarkar, Margaret A. McLaughlin, David O. Meltzer (2009-06-22). "Frequency of Failure to Inform Patients of Clinically Significant Outpatient Test Results". Arch Intern Med 169 (12): 1123-1129. DOI:10.1001/archinternmed.2009.130. Retrieved on 2009-06-23. Research Blogging.
  37. Friedberg MW, Coltin KL, Safran DG, Dresser M, Zaslavsky AM, Schneider EC (2009). "Associations between structural capabilities of primary care practices and performance on selected quality measures.". Ann Intern Med 151 (7): 456-63. PMID 19805769.
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  39. Jha AK, DesRoches CM, Campbell EG, Donelan K, Rao SR, Ferris TG et al. (2009). "Use of electronic health records in U.S. hospitals.". N Engl J Med 360 (16): 1628-38. DOI:10.1056/NEJMsa0900592. PMID 19321858. Research Blogging.
  40. Brown SH, Lincoln MJ, Groen PJ, Kolodner RM (2003). "VistA--U.S. Department of Veterans Affairs national-scale HIS". International journal of medical informatics 69 (2-3): 135–56. PMID 12810119[e]
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  44. Littlejohns P, Wyatt JC, Garvican L (2003). "Evaluating computerised health information systems: hard lessons still to be learnt". BMJ 326 (7394): 860–3. DOI:10.1136/bmj.326.7394.860. PMID 12702622. Research Blogging.
  45. DesRoches CM, Campbell EG, Rao SR, Donelan K, Ferris TG, Jha A et al. (2008). "Electronic health records in ambulatory care--a national survey of physicians.". N Engl J Med 359 (1): 50-60. DOI:10.1056/NEJMsa0802005. PMID 18565855. Research Blogging.
  46. Baron RJ, Fabens EL, Schiffman M, Wolf E (2005). "Electronic health records: just around the corner? Or over the cliff?". Ann Intern Med 143 (3): 222-6. PMID 16061920.
  47. Baron RJ (2007). "Quality improvement with an electronic health record: achievable, but not automatic.". Ann Intern Med 147 (8): 549-52. PMID 17938393.
  48. Details for: CMS PROPOSES DEFINITION OF MEANINGFUL USE OF CERTIFIED ELECTRONIC HEALTH RECORDS (EHR) TECHNOLOGY Department of Health and Human Services
  49. Proposed Rules Regulations.gov
  50. Jha, Ashish K. (2010-10-20). "Meaningful Use of Electronic Health Records: The Road Ahead". JAMA 304 (15): 1709-1710. DOI:10.1001/jama.2010.1497. Retrieved on 2010-10-21. Research Blogging.
  51. Kibbe DC. (2010) Should Doctors Reject the Government's EHR Incentive Plan?
  52. Morrison, Frances P.; Li Li, Albert M. Lai, George Hripcsak (2008-10-24). "Repurposing the clinical record: can an existing natural language processing system de-identify clinical notes?". J Am Med Inform Assoc: M2862. DOI:10.1197/jamia.M2862. Retrieved on 2008-10-27. Research Blogging.