Normal weight obesity: Difference between revisions

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The prevalence of obesity has risen rapidly over the years and shows no clear signs of slowing down. A great epidemiological representation of that can be seen in studies using the population of the US of A, collected from the 1960s to present time. It has shown that obesity in the population has increased from ~13% to almost 30%.<ref>Romero-Corral A ''et al.'' (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality'' Eur Heart J'' 31:737-46 PMID 19933515</ref>
The prevalence of obesity has risen rapidly over the years and shows no clear signs of slowing down. A great epidemiological representation of that can be seen in studies using the population of the US of A, collected from the 1960s to present time. It has shown that obesity in the population has increased from ~13% to almost 30%.<ref>Romero-Corral A ''et al.'' (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality'' Eur Heart J'' 31:737-46 PMID 19933515</ref>


To clinically classify a person as being obese, their Body Mass Index (BMI) must be equal to or greater than 30kg/m2. However, the spectrum of obesity is quite large. '''Normal Weight Obesity (NWO)''', found in almost half of the American adult population, is when a person has a normal BMI or normal body weight but also has a high percentage of '''body [[adipocyte|fat]]'''(>20% for men and >30% for women) as well as heart and metabolic disturbances. <ref>Romero-Corral A ''et al.'' (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality'' Eur Heart J'' 31:737-46 PMID 19933515</ref>  
To clinically classify a person as being obese, their Body Mass Index (BMI) must be equal to or greater than 30kg/m2. However, the spectrum of obesity is quite large. '''Normal Weight Obesity (NWO)''', found in almost half of the American adult population, is when a person has a normal BMI (18.5- 24.9 kg/m2) or normal body weight but also has a high percentage of '''body [[adipocyte|fat]]'''(>23.1% for men and >33.3% for women) as well as heart and metabolic disturbances. <ref>Romero-Corral A ''et al.'' (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality'' Eur Heart J'' 31:737-46 PMID 19933515</ref>  




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The strong relationship between high Adiposity and metabolic disturbances makes it vital to try find a more accurate way in which to determine adiposity other than BMI.
The strong relationship between high Adiposity and metabolic disturbances makes it vital to try find a more accurate way in which to determine adiposity other than BMI.
The definition of metabolic syndrome covers the following criteria's:
1) Waist circumference (>102 in men and >88 in women)
2)HDL (<1.04mmol/L in men and <1.03mmol/L in women)
3)Triglycerides (>1.7mmol/L)
4)Blood Pressure (systolic blood pressure >130mmHg or diastolic blood pressure >85mmHg)
5)Fasting Glucose (>5.5mmol/L)


== '''Genetic links''' ==
== '''Genetic links''' ==

Revision as of 10:37, 25 October 2011

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The prevalence of obesity has risen rapidly over the years and shows no clear signs of slowing down. A great epidemiological representation of that can be seen in studies using the population of the US of A, collected from the 1960s to present time. It has shown that obesity in the population has increased from ~13% to almost 30%.[1]

To clinically classify a person as being obese, their Body Mass Index (BMI) must be equal to or greater than 30kg/m2. However, the spectrum of obesity is quite large. Normal Weight Obesity (NWO), found in almost half of the American adult population, is when a person has a normal BMI (18.5- 24.9 kg/m2) or normal body weight but also has a high percentage of body fat(>23.1% for men and >33.3% for women) as well as heart and metabolic disturbances. [2]


Measuring Normal Weight Obesity

Sawdah Jakda 16:04, 25 October 2011 (UTC)

The gold standard definition of obesity is considered to be an excess in Body Fat (BF) but the BMI is used by clinicians and epidemiologists as a means of defining the presence of adiposity and/or obesity. The advantages of using the BMI instead of BF values is that it is a lot more simple to use and it is easy to reproduce. Studies showing the association between extreme BMI values and increased mortality further support its usage. However, this test fails to differentiate between elevated BF content and preserved/ increased lean mass in patient with a BMI below 30kg/m2, those not clinically classified as obese.

The strong relationship between high Adiposity and metabolic disturbances makes it vital to try find a more accurate way in which to determine adiposity other than BMI.

The definition of metabolic syndrome covers the following criteria's:

1) Waist circumference (>102 in men and >88 in women)

2)HDL (<1.04mmol/L in men and <1.03mmol/L in women)

3)Triglycerides (>1.7mmol/L)

4)Blood Pressure (systolic blood pressure >130mmHg or diastolic blood pressure >85mmHg)

5)Fasting Glucose (>5.5mmol/L)


Genetic links

Disorders linked to NWO

Treatments and Prevention

Conclusion

References

  1. Romero-Corral A et al. (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality Eur Heart J 31:737-46 PMID 19933515
  2. Romero-Corral A et al. (2010) Normal weight obesity: a risk factor for cardiometabolic dysregulation and cardiovascular mortality Eur Heart J 31:737-46 PMID 19933515