Ibuprofen: Difference between revisions

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{{Image|Ibuprofen.png|right|200px|'''Ibuprofen'''}}
{{Image|Ibuprofen.png|right|200px|'''Ibuprofen'''}}
'''Ibuprofen''' is an analgesic drug and a member of the class of drugs refered to as [[non-steroidal anti-inflammatory drugs]] (NSAIDS). It is thought to be a [[cyclooxygenase]] (COX) inhibitor, and, like other NSAIDS, may lead to discomfort and ulceration of the [[gastrointestinal tract]].  
'''Ibuprofen''' is an analgesic drug and a member of the class of drugs refered to as [[non-steroidal anti-inflammatory agent|non-steroidal anti-inflammatory drugs]] (NSAIDS). It is thought to be a nonselective [[cyclooxygenase]] (COX) inhibitor, and, like other NSAIDS, may lead to discomfort and ulceration of the [[gastrointestinal tract]].  


== Chemistry ==
== Chemistry ==
The form used as a drug is formally the (S)-(+)-Ibuprofen [[isomer]], although it may be sold as a racemic mixture. It is also called other names, including (2S)-2-[4-(2-Methylpropyl)phenyl]propionic acid, (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid, and (S)-(+)-2-(4-Isobutylphenyl)propionic acid. It has a molecular formula of C<sub>13</sub>H<sub>18</sub>O<sub>2</sub> and a molecular mass of 206.28 [[gram]]s/[[mole]].
Along with [[naproxen]], it is the NSAID class called the propionic acid derivatives. The form used as a drug is formally the (S)-(+)-Ibuprofen [[isomer]], although it may be sold as a racemic mixture. It is also called other names, including (2S)-2-[4-(2-Methylpropyl)phenyl]propionic acid, (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid, and (S)-(+)-2-(4-Isobutylphenyl)propionic acid.  
 
It has a molecular formula of C<sub>13</sub>H<sub>18</sub>O<sub>2</sub> and a molecular mass of 206.28 [[gram]]s/[[mole]].

Revision as of 19:31, 19 March 2011

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© Drawing: David E. Volk
Ibuprofen

Ibuprofen is an analgesic drug and a member of the class of drugs refered to as non-steroidal anti-inflammatory drugs (NSAIDS). It is thought to be a nonselective cyclooxygenase (COX) inhibitor, and, like other NSAIDS, may lead to discomfort and ulceration of the gastrointestinal tract.

Chemistry

Along with naproxen, it is the NSAID class called the propionic acid derivatives. The form used as a drug is formally the (S)-(+)-Ibuprofen isomer, although it may be sold as a racemic mixture. It is also called other names, including (2S)-2-[4-(2-Methylpropyl)phenyl]propionic acid, (S)-(+)-4-Isobutyl-alpha-methylphenylacetic acid, and (S)-(+)-2-(4-Isobutylphenyl)propionic acid.

It has a molecular formula of C13H18O2 and a molecular mass of 206.28 grams/mole.