Glucuronosyltransferase: Difference between revisions
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imported>Robert Badgett (New page: In biochemistry, '''glucuronosyltransferase''', also called UDP-glucuronosyltransferase, is "a family of enzymes accepting a wide range of substrates, including phenols, alcohols, ami...) |
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In [[biochemistry]], '''glucuronosyltransferase''', also called UDP-glucuronosyltransferase, is "a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of [[UDPglucuronic acid]] to a variety of endogenous and exogenous compounds."<ref>{{MeSH}}</ref> | In [[biochemistry]], '''glucuronosyltransferase''', also called UDP-glucuronosyltransferase, is "a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of [[UDPglucuronic acid]] to a variety of endogenous and exogenous compounds."<ref>{{MeSH}}</ref> | ||
Mutation in the UDP-glycuronosyltransferase gene cause [[Gilbert Syndrome]]<ref>{{OMIM|143500}}</ref> and [[Crigler-Najjar Syndrome]] types I<ref>{{OMIM|218800}}</ref> and II<ref>{{OMIM|606785}}</ref>. | |||
==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 12:06, 8 April 2010
In biochemistry, glucuronosyltransferase, also called UDP-glucuronosyltransferase, is "a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds."[1]
Mutation in the UDP-glycuronosyltransferase gene cause Gilbert Syndrome[2] and Crigler-Najjar Syndrome types I[3] and II[4].
References
- ↑ Anonymous (2024), Glucuronosyltransferase (English). Medical Subject Headings. U.S. National Library of Medicine.
- ↑ Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 143500. World Wide Web URL: http://omim.org/.
- ↑ Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 218800. World Wide Web URL: http://omim.org/.
- ↑ Online Mendelian Inheritance in Man, OMIM®. Johns Hopkins University, Baltimore, MD. MIM Number: 606785. World Wide Web URL: http://omim.org/.