Xanthine: Difference between revisions
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'''Xanthine''' is a purine base found in most body tissues and fluids, certain plants, and some urinary calculi. <ref>{{MeSH}}</ref> | |||
It is an intermediate in the degradation of [[adenosine monophosphate]] to [[uric acid]], being formed by oxidation of hypoxanthine. Thus, [[Gout#Xanthine oxidase inhibitors|inhibition of xanthine oxidase]], by drugs such as [[allopurinol]] is a treatment for [[gout]], caused by increases of uric acid crystals in tissue. | |||
The [[methylxanthines]] [[caffeine]], [[theobromine]], and [[theophylline]] and their derivatives are used in medicine for their [[bronchodilator]] and stimulant effects. | |||
==References== | |||
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Latest revision as of 17:29, 4 November 2010
Xanthine is a purine base found in most body tissues and fluids, certain plants, and some urinary calculi. [1]
It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. Thus, inhibition of xanthine oxidase, by drugs such as allopurinol is a treatment for gout, caused by increases of uric acid crystals in tissue.
The methylxanthines caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator and stimulant effects.
References
- ↑ Anonymous (2024), Xanthine (English). Medical Subject Headings. U.S. National Library of Medicine.