Tetrazole: Difference between revisions
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'''Tetrazoles''' are cyclic chemical compounds having a base structure (C<sub>1</sub>N<sub>4</sub>H<sub>2</sub>) in which four nitrogen atoms and one carbon atom form a 5-atom heterocycle. They can be synthesized by reacting a [[cyanide]] with an [[azide]], as depicted below. The base tetrazole compound (R<sub>1</sub> = R<sub>2</sub> = H) is commonly used as a [[base (chemistry)|base]] in chemical reactions. Some tetrazoles are [[angiotensin]] receptor antagonists used to treat high blood pressure ([[hypertension]]). | '''Tetrazoles''' are cyclic chemical compounds having a base structure (C<sub>1</sub>N<sub>4</sub>H<sub>2</sub>) in which four nitrogen atoms and one carbon atom form a 5-atom heterocycle. They can be synthesized by [[click chemistry]], reacting a [[cyanide]] with an [[azide]], as depicted below. The base tetrazole compound (R<sub>1</sub> = R<sub>2</sub> = H) is commonly used as a [[base (chemistry)|base]] in chemical reactions. Some tetrazoles are [[angiotensin]] receptor antagonists used to treat high blood pressure ([[hypertension]]). | ||
{{Image|Tetrazole Click chemistry.png|right|350px|Tetrazole formed by cyclization of a cyanide and an azide.}} | {{Image|Tetrazole Click chemistry.png|right|350px|Tetrazole formed by cyclization of a cyanide and an azide.}} | ||
Revision as of 14:38, 6 February 2010
Tetrazoles are cyclic chemical compounds having a base structure (C1N4H2) in which four nitrogen atoms and one carbon atom form a 5-atom heterocycle. They can be synthesized by click chemistry, reacting a cyanide with an azide, as depicted below. The base tetrazole compound (R1 = R2 = H) is commonly used as a base in chemical reactions. Some tetrazoles are angiotensin receptor antagonists used to treat high blood pressure (hypertension).
