Cirrhosis: Difference between revisions
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'''Cirrhosis''' is a "liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules."<ref name="title">{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?mode=&term=Liver+Cirrhosis |title=Liver cirrhosis |accessdate=2008-01-07 |author=Anonymous |authorlink= |coauthors= |date= |format= |work= |publisher=National Library of Medicine |pages= |language= |archiveurl= |archivedate= |quote=}}</ref> | '''Cirrhosis''' is a "liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules."<ref name="title">{{cite web |url=http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?mode=&term=Liver+Cirrhosis |title=Liver cirrhosis |accessdate=2008-01-07 |author=Anonymous |authorlink= |coauthors= |date= |format= |work= |publisher=National Library of Medicine |pages= |language= |archiveurl= |archivedate= |quote=}}</ref> | ||
==Complications== | |||
===Ascites=== | |||
{{main|Ascites}} | |||
===Hepatic encephalopathy=== | |||
{{main|Hepatic encephalopathy}} | |||
==Prognosis== | ==Prognosis== | ||
Revision as of 16:43, 8 January 2008
Cirrhosis is a "liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules."[1]
Complications
Ascites
Hepatic encephalopathy
Prognosis
MELD Score
The MELD Score can help predict mortality. An online calculator is available.
In interpeting the MELD Score in hospitalized patients, the 3 month mortality is:[2]
- 40 or more - 100% mortality
- 30-39 - 83% mortality
- 20-29 - 76% mortality
- 10-19 - 27% mortality
- <10 - 4% mortality
The MELD has also been studied in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS).[3]
References
- ↑ Anonymous. Liver cirrhosis. National Library of Medicine. Retrieved on 2008-01-07.
- ↑ Kamath PS, Wiesner RH, Malinchoc M, et al (2001). "A model to predict survival in patients with end-stage liver disease". Hepatology 33 (2): 464–70. DOI:10.1053/jhep.2001.22172. PMID 11172350. Research Blogging.
- ↑ Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC (2000). "A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts". Hepatology 31 (4): 864–71. DOI:10.1053/he.2000.5852. PMID 10733541. Research Blogging.